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Saturday, June 16, 2007

Hepatitis A - Vaccine

Hepatitis is inflammation of the liver. The hepatitis A vaccine protects you against one type of hepatitis, hepatitis A. The vaccine stimulates your body to produce antibodies against the hepatitis A virus. Note that this vaccine will not protect you from other types of hepatitis.

The vaccine, called Havrix or VAQTA, is made from inactivated whole virus of hepatitis A. It is given by an injection in your arm. You should be protected against the disease within two weeks after receiving the first injection.

To ensure complete immunization against the disease, two vaccinations are required. After receiving the first vaccination, children and adults should have a booster vaccination in 6 to 12 months.

There is also a vaccine for adults called Twinrix that contains both Hepatitis A and B in combination. It reduces the number of needle sticks to achieve immunity to both viruses. It is given in 3 doses.

WHO SHOULD BE IMMUNIZED

People who work or travel in areas with high rates of infection should be vaccinated. These areas include Africa, Asia (except Japan), the Mediterranean, Eastern Europe, the Middle East, Central and Southern America, Mexico, and parts of the Caribbean.


If you are traveling to these areas before you are fully immunized (less than 4 weeks after first immunization), you should receive a preventive dose of immunoglobulin (IG). If you are just a short-term traveler to these areas, you may wish to only receive the immunoglobulin (IG) instead of the vaccine.

This vaccine is mandated (required) in children in Alaska, Arizona, Missouri, Nevada, New Mexico, Oklahoma, Tennessee, and Utah. In addition, the ACIP recommends vaccination in children in California, Montana, Idaho, Oregon, and Washington. These recommendations are based on the number of cases of Hepatitis in these states.

Other people who are at higher risk for hepatitis A include:

  • Illegal intravenous drug users.
  • People who work with the hepatitis A virus in a laboratory or with primates that may be infected with the virus.
  • People who have chronic liver disease.
  • People who receive clotting factor concentrate to treat hemophilia or other clotting disorders.
  • Military personnel.
  • Homosexual or bisexual men.
  • Employees of child day-care centers.
  • People who care for institutionalized patients.

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